Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbiOABC transporter ATP-binding protein-cobalt transport; COG1122, CbiO, ABC-type cobalt transport system. (560 aa)    
Predicted Functional Partners:
cbiQ
ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.
 
 0.997
smi_1811
Conserved hypothetical protein.
 
  
 0.972
ecfT
ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 0.898
smi_1812
Conserved hypothetical protein.
 
     0.889
amiC
ABC transporter membrane-spanning permease-oligopeptide transport.
  
 
 0.825
amiD
ABC transporter membrane-spanning permease-oligopeptide transport.
  
 
 0.757
ecfA
ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
 
0.700
ecfA-2
ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
 
0.700
smi_0291
Substrate-binding lipoprotein, oligopeptide transport.
  
 0.553
amiA
ABC transporter substrate-binding protein-oligopeptide transport.
  
 0.553
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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