Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_1811Conserved hypothetical protein. (181 aa)    
Predicted Functional Partners:
cbiO
ABC transporter ATP-binding protein-cobalt transport; COG1122, CbiO, ABC-type cobalt transport system.
 
  
 0.972
cbiQ
ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.
 
 
 0.966
smi_1812
Conserved hypothetical protein.
 
     0.955
ecfT
ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
 
 0.589
smi_1950
Transcriptional regulator; Cd00093, Helix-turn-helix XRE-family like proteins.
  
     0.509
trkA2
Potassium uptake protein; COG0569, TrkA, K+ transport system, NAD-binding component.
       0.489
trkG2
Potassium uptake protein; COG0168, TrkG, Trk-type K+ transport system, membrane component.
       0.489
smi_1941
ABC transporter permease; COG 2011, metal ion transport.
  
    0.470
sstT
Predicted Na+/serine symporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.461
metN
ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
       0.461
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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