Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_1869Transcriptional regulator; Pfam04397, LytTr DNA-binding domain. (151 aa)    
Predicted Functional Partners:
smi_1870
ABC tranporter, permease; COG0842, multidrug transport system.
 
   
 0.961
smi_1871
ABC tranporter, ATP-binding protein; COG1131, CcmA, multidrug transport system.
 
     0.957
smi_1868
Conserved hypothetical protein.
       0.865
smi_1933
Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.
  
   
 0.684
smi_1832
Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.
  
   
 0.591
smi_1867
Pfam00583, acetyltransferase (GNAT) family.
  
    0.550
smi_1866
Pfam00583, acetyltransferase (GNAT) family.
       0.528
rpmH
50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
       0.461
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.402
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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