Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
smi_1911Conserved hypothetical protein. (46 aa)    
Predicted Functional Partners:
nrdD
Anaerobic ribonucleotide reductase; COG1328, NrdD, oxygen-sensitive ribonucleoside-triphosphate reductase.
       0.781
smi_1910
Acetyltransferase; COG3981.
       0.662
smi_1908
Conserved hypothetical protein; Pfam00485, PRK, phosphoribulokinase / uridine kinase family.
       0.643
nrdG
NrdD activating enzymeanaerobic ribonucleoside-triphosphate reductase activator; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
       0.643
ccs4
Competence-induced protein Ccs4.
       0.510
smi_1914
Conserved hypothetical protein; Orf47, induced duriong competence in Streptococcus pneumoniae.
       0.438
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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