smi_1932 protein (Streptococcus mitis) - STRING interaction network

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Score

smi_1932

Conserved hypothetical protein. (31 aa)

Predicted Functional Partners:

hexB

0.718

tag

0.689

ruvA

0.689

smi_1933

0.548

smi_1934

0.548

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hexB	ruvA	smi_1931	smi_1930	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	0.951
hexB	smi_1932	smi_1931	smi_1932	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	Conserved hypothetical protein.	0.718
hexB	smi_1933	smi_1931	smi_1933	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	0.722
hexB	smi_1934	smi_1931	smi_1934	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	Conserved hypothetical protein.	0.722
hexB	tag	smi_1931	smi_1929	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	Pfam03352, methyladenine glycosylase.	0.862
ruvA	hexB	smi_1930	smi_1931	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.951
ruvA	smi_1932	smi_1930	smi_1932	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	Conserved hypothetical protein.	0.689
ruvA	smi_1933	smi_1930	smi_1933	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	0.548
ruvA	smi_1934	smi_1930	smi_1934	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	Conserved hypothetical protein.	0.609
ruvA	tag	smi_1930	smi_1929	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	Pfam03352, methyladenine glycosylase.	0.901
smi_1932	hexB	smi_1932	smi_1931	Conserved hypothetical protein.	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.718
smi_1932	ruvA	smi_1932	smi_1930	Conserved hypothetical protein.	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	0.689
smi_1932	smi_1933	smi_1932	smi_1933	Conserved hypothetical protein.	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	0.548
smi_1932	smi_1934	smi_1932	smi_1934	Conserved hypothetical protein.	Conserved hypothetical protein.	0.548
smi_1932	tag	smi_1932	smi_1929	Conserved hypothetical protein.	Pfam03352, methyladenine glycosylase.	0.689
smi_1933	hexB	smi_1933	smi_1931	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	DNA mismatch repair protein hexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.722
smi_1933	ruvA	smi_1933	smi_1930	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	Holiday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	0.548
smi_1933	smi_1932	smi_1933	smi_1932	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	Conserved hypothetical protein.	0.548
smi_1933	smi_1934	smi_1933	smi_1934	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	Conserved hypothetical protein.	0.934
smi_1933	tag	smi_1933	smi_1929	Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.	Pfam03352, methyladenine glycosylase.	0.537