Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_1940Conserved hypothetical protein. (189 aa)    
Predicted Functional Partners:
smi_1939
Conserved hypothetical protein; COG5578, predicted integral membrane proteins.
       0.541
smi_1938
COG2972, sensor histidine kinase, two component regulatory system; signal transduction proteins with a C-terminal ATPase domain.
       0.531
smi_1937
COG 4753, two component regulatory system, response regulators containing CheY-like receiver domain and AraC-type DNA-binding domain.
       0.524
smi_0786
Conserved hypothetical protein; Pfam06970, RepA_N, replication initiator protein A (RepA) N-terminus.
  
     0.490
smi_1943
Deacylase; COG0624, acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase /and related deacylases; peptidase family M20. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are glutamate carboxypeptidases.
       0.460
smi_1812
Conserved hypothetical protein.
       0.445
smi_1941
ABC transporter permease; COG 2011, metal ion transport.
       0.436
metN
ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
       0.436
smi_1811
Conserved hypothetical protein.
       0.432
pcnB
tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
      
 0.428
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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