Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_1944ABC transporter substrate-binding lipoprotein; COG1464, ABC-type metal ion transport system; Belongs to the nlpA lipoprotein family. (284 aa)    
Predicted Functional Partners:
smi_1941
ABC transporter permease; COG 2011, metal ion transport.
 0.999
metN
ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
 0.997
smi_1943
Deacylase; COG0624, acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase /and related deacylases; peptidase family M20. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are glutamate carboxypeptidases.
       0.730
smi_1945
ABC transporter substrate-binding lipoprotein; Pfam00497, bacterial extracellular solute-binding proteins.
  
  
 0.553
smi_1010
O-acetylhomoserine sulfhydrylase.
  
    0.536
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.453
metF
5,10-methylenetetrahydrofolate reductase; COG0685; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.405
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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