Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_1952Acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (145 aa)    
Predicted Functional Partners:
smi_1953
Molecular chaperone; COG1214, inactive homolog of metal-dependent proteases.
  
 
 0.970
tsaD
Metal-dependent protease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
  
 0.904
smi_1947
Conserved hypothetical protein; COG4392, membrane protein.
       0.562
smi_1950
Transcriptional regulator; Cd00093, Helix-turn-helix XRE-family like proteins.
  
    0.544
smi_1948
Branched-chain amino acid permease; COG1296, AzlC protein.
       0.504
tnpA-42
Transposase, ISSmi1; COG2826, IS30 family.
       0.499
smi_1959
Conserved hypothetical protein; Belongs to the UPF0356 family.
       0.461
rnj-2
Hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.461
smi_1843
Conserved hypothetical protein; COG0802, predicted ATPase or kinase.
  
  
 0.436
galK
Galactokinase, (galactose kinase); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
  
    0.411
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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