Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
argGArgininosuccinate synthase; COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (398 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase; COG0165.
 
 
 0.999
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
 
 
 0.985
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.921
carA
Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
  
 
 0.915
asnA
Aspartate--ammonia ligase (asparagine synthetase A).
   
 
 0.911
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.908
smi_1969
ABC transporter substrate-binding protein; Pfam00497, bacterial extracellular solute-binding proteins, family 3.
  
  
 0.908
ansB
L-asparaginase (L-asparagine amidohydrolase).
   
 
 0.903
ahrC
Transcriptional repressor protein; Regulates arginine biosynthesis genes.
  
  
 0.891
argR2
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.886
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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