Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1990Conserved hypothetical protein; Cd01518, rhodanese homology domain superfamily; Belongs to the UPF0176 family. (343 aa)    
Predicted Functional Partners:
smi_1989
Conserved hypothetical protein.
       0.668
smi_1155
Conserved hypothetical protein; COG4109, predicted transcriptional regulator containing CBS domains.
      
 0.599
smi_1920
Conserved hypothetical protein; Belongs to the UPF0297 family.
      
 0.599
smi_2070
Conserved hypothetical protein.
     
 0.599
smi_1991
Conserved hypothetical protein; Related to bacteriocin immunity proteins.
       0.547
smi_0377
Nucleic-acid-binding protein implicated in transcription termination.
      
 0.531
smi_0388
COG0703, shikimate kinase.
  
     0.446
shetA
Exfoliative toxin A.
       0.436
pncO
Metal-dependent CAAX amino terminal membrane protease family protein; Pfam02517.
       0.432
smi_1532
Transcriptional regulator.
  
     0.401
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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