Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
pncOMetal-dependent CAAX amino terminal membrane protease family protein; Pfam02517. (229 aa)    
Predicted Functional Partners:
pncQ
Bacteriocin immunity protein; Two TM-helices predicted.
     
 0.615
smi_1672
Metal-dependent CAAX amino terminal membrane protease family protein; Pfam02517.
  
     0.598
smi_1991
Conserved hypothetical protein; Related to bacteriocin immunity proteins.
       0.592
spiR2
Response regulator.
      
 0.522
aspC1
Aspartate aminotransferase.
      
 0.499
smi_1870
ABC tranporter, permease; COG0842, multidrug transport system.
  
    0.475
smi_1990
Conserved hypothetical protein; Cd01518, rhodanese homology domain superfamily; Belongs to the UPF0176 family.
       0.432
aspC2
Aspartate aminotransferase.
      
 0.425
smi_1993
ABC transporter substrate-binding protein.
  
    0.404
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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