Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1999Conserved hypothetical protein. (426 aa)    
Predicted Functional Partners:
smi_1998
COG0383, alpha-mannosidase.
 
  
 0.968
smi_2018
Sugar hydrolase; COG3537, alpha-1,2-mannosidase.
  
 0.948
smi_1996
Glycosyl hydrolase family 20 (GH20) protein.
 
   
 0.919
smi_1993
ABC transporter substrate-binding protein.
 
   
 0.872
smi_1995
ABC transporter permease, sugar transport; COG1175; ABC-type polysaccharide transport system.
 
   
 0.791
smi_1994
COG0395, UgpE, ABC-type sugar transport system.
 
   
 0.785
smi_1939
Conserved hypothetical protein; COG5578, predicted integral membrane proteins.
 
   
 0.770
smi_1997
Fam00480, ROK family.
     
 0.688
smi_2019
Fucosidase; COG3669, alpha-L-fucosidase.
 
   
 0.617
bgaA
Beta-galactosidase; LPXTG motif.
 
     0.612
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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