Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_2020Hypothetical protein. (424 aa)    
Predicted Functional Partners:
smi_2021
Beta-galactosidase/beta-glucuronidase, truncated; COG3250; Belongs to the glycosyl hydrolase 2 family.
     0.899
smi_2019
Fucosidase; COG3669, alpha-L-fucosidase.
 
   
 0.860
smi_1537
N-acetyl-beta-hexosaminidase; COG3525, LPXTG motif.
 
 
 0.459
ptsG
PTS glucose-specific enzyme IIABC component.
  
  
 0.441
smi_1615
PTS system; COG1263.
  
  
 0.441
smi_1701
Hypothetical protein.
  
     0.413
smi_2022
Conserved hypothetical protein.
    
  0.412
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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