Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glpDGlycerol-3-phosphate dehydrogenase; COG0578. (608 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 0.999
gpdA
Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.925
glpF
Glycerol uptake facilitator protein; Cd00333, major intrinsic protein (MIP) superfamily; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 0.919
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
     
 0.910
smi_0661
1-acylglycerol-3-phosphate O-acyltransferase.
  
 
 0.829
smi_1052
Dihydroxyacetone kinase; COG2376, DAK1.
  
 
 0.814
smi_1051
Dihydroxyacetone kinase; COG2376, DAK1.
  
 
 0.812
smi_2036
Regulatory protein.
 
     0.722
smi_1347
Glycerol uptake facilitator paralog; Cd00333, Major intrinsic protein (MIP) superfamily; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.653
smi_0568
Aquaporin Z-water channel protein; Cd00333, MIP, Major intrinsic protein (MIP) superfamily; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
 0.606
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.