Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (502 aa)    
Predicted Functional Partners:
glpD
Glycerol-3-phosphate dehydrogenase; COG0578.
 0.999
htrA
COG0265, trypsin-like serine proteases.
   
 0.942
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.923
glpF
Glycerol uptake facilitator protein; Cd00333, major intrinsic protein (MIP) superfamily; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.919
smi_1347
Glycerol uptake facilitator paralog; Cd00333, Major intrinsic protein (MIP) superfamily; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.870
ptsG
PTS glucose-specific enzyme IIABC component.
  
 
 0.820
smi_1615
PTS system; COG1263.
  
 
 0.820
smi_1463
ATPases of the AAA+ class; COG0464.
   
  0.734
smi_0568
Aquaporin Z-water channel protein; Cd00333, MIP, Major intrinsic protein (MIP) superfamily; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.678
fruA
PTS system, fructose specific IIBC component.
   
  
 0.677
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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