Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_2042Conserved hypothetical protein. (257 aa)    
Predicted Functional Partners:
pnuC
Nicotinamide mononucleotide transporter; COG3201, PnuC.
     
 0.875
nadR
Bifunctional NadR protein; COG3172, NadR, predicted ATPase/kinase involved in NAD metabolism.
       0.865
ctsR
Pfam05848, firmicute transcriptional repressor of class III stress genes (CtsR); Belongs to the CtsR family.
     
 0.689
clpC
COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
    0.679
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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