Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
smi_2059Conserved hypothetical protein. (211 aa)    
Predicted Functional Partners:
hpf
Ribosome-associated protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
     
 0.832
comFA
Helicase ComFA; COG4098, superfamily II DNA/RNA helicase required for DNA uptake.
     
 0.763
comFC
ComFC protein; COG1040, predicted amidophosphoribosyltransferases, involved in transformation.
       0.747
cysK
Cysteine synthase; COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
   0.730
smi_0731
Conserved hypothetical protein; COG0144, sun, tRNA and rRNA cytosine-C5-methylases [.
   
  
 0.550
smi_0362
ABC transporter membrane-spanning permease.
      
 0.537
smi_0730
Cd01637, IMPase_like, inositol-monophosphatase-like domains.
      
 0.522
smi_0921
Membrane protein; COG0628, PerM, predicted permease.
     
 0.514
smi_1301
Conserved hypothetical protein; COG0628, predicted permease.
     
 0.514
smi_0664
Bcl-2 family protein; COG2384, SAM-dependent methyltransferase.
   
    0.445
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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