mreD protein (Streptococcus mitis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

mreD

Cell shape determining protein MreD; COG2891. (164 aa)

Predicted Functional Partners:

mreC

0.998

pgsA

0.870

rodA

0.822

smi_2070

0.798

gpsB

0.782

ecfT

0.761

ecfA

0.761

ecfA-2

0.761

pbp2B

0.757

ftsW

0.754

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ecfA	ecfA-2	smi_2067	smi_2068	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA	ecfT	smi_2067	smi_2066	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA	mreC	smi_2067	smi_2065	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Cell shape determining protein MreC; Involved in formation and maintenance of cell shape.	0.774
ecfA	mreD	smi_2067	smi_2064	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Cell shape determining protein MreD; COG2891.	0.761
ecfA	pgsA	smi_2067	smi_2069	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Phosphatidylglycerophosphate synthase; COG0558, PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.879
ecfA	smi_2070	smi_2067	smi_2070	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein.	0.863
ecfA-2	ecfA	smi_2068	smi_2067	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA-2	ecfT	smi_2068	smi_2066	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA-2	mreC	smi_2068	smi_2065	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Cell shape determining protein MreC; Involved in formation and maintenance of cell shape.	0.774
ecfA-2	mreD	smi_2068	smi_2064	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Cell shape determining protein MreD; COG2891.	0.761
ecfA-2	pgsA	smi_2068	smi_2069	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Phosphatidylglycerophosphate synthase; COG0558, PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.878
ecfA-2	smi_2070	smi_2068	smi_2070	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein.	0.863
ecfT	ecfA	smi_2066	smi_2067	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfT	ecfA-2	smi_2066	smi_2068	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfT	mreC	smi_2066	smi_2065	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Cell shape determining protein MreC; Involved in formation and maintenance of cell shape.	0.788
ecfT	mreD	smi_2066	smi_2064	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Cell shape determining protein MreD; COG2891.	0.761
ecfT	pgsA	smi_2066	smi_2069	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Phosphatidylglycerophosphate synthase; COG0558, PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.872
ecfT	smi_2070	smi_2066	smi_2070	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein.	0.863
ftsW	gpsB	smi_0984	smi_1754	Cell division protein FtsW; Belongs to the SEDS family.	Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.	0.447
ftsW	mreC	smi_0984	smi_2065	Cell division protein FtsW; Belongs to the SEDS family.	Cell shape determining protein MreC; Involved in formation and maintenance of cell shape.	0.821