STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Csa_2G005350tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (493 aa)    
Predicted Functional Partners:
Csa_2G368930
Uncharacterized protein.
   
 
 0.834
Csa_6G513770
SAM_MT_TRM5_TYW2 domain-containing protein.
  
 
0.739
Csa_6G140820
C3H1-type domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
  
 0.657
Csa_1G173210
SAM-dependent MTase TRM10-type domain-containing protein.
   
  
 0.636
Csa_6G497190
tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.
   
  
 0.595
Csa_3G732420
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
   
  
 0.579
Csa_2G367740
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
   
  
 0.577
Csa_1G555080
Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family.
   
  
 0.570
Csa_7G229890
Uncharacterized protein.
   
  
 0.511
Csa_5G517870
Peptidase_M22 domain-containing protein.
   
  
 0.487
Your Current Organism:
Cucumis sativus
NCBI taxonomy Id: 3659
Other names: C. sativus, Cucumis sativus L., cucumber, cucumbers
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