STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Csa_1G399640Uncharacterized protein. (139 aa)    
Predicted Functional Partners:
Csa_3G813290
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.955
Csa_3G172970
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.929
Csa_4G188670
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.926
Csa_4G188795
Helicase ATP-binding domain-containing protein.
    
 0.926
Csa_4G188732
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.926
Csa_5G623550
ERCC4 domain-containing protein.
    
 0.884
Csa_3G912890
ERCC4 domain-containing protein.
    
 0.835
Csa_2G058700
RECA_2 domain-containing protein.
    
 0.719
Csa_3G127240
Uncharacterized protein.
   
 
 0.718
Csa_3G129670
Zinc-hook domain-containing protein.
    
 0.703
Your Current Organism:
Cucumis sativus
NCBI taxonomy Id: 3659
Other names: C. sativus, Cucumis sativus L., cucumber, cucumbers
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