STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_0639Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMc02367 putative sensor histidine kinase transmembrane protein. (465 aa)    
Predicted Functional Partners:
Smed_0638
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc02366 putative transcription regulator protein.
 
 0.971
Smed_0630
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc00458 probable transcription regulator protein.
 
 0.837
Smed_2245
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc01593 putative transcription regulator protein.
 
 0.750
Smed_0124
Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc02140 phosphate regulon transcriptional regulatory protein.
 
 0.745
Smed_0925
PFAM: response regulator receiver; KEGG: sme:SMc01371 putative 2-component receiver domain protein.
 
 
 
 0.684
Smed_3056
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc03820 putative transcription regulator protein.
 
 0.677
Smed_2605
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc00654 response regulator,controls chromosomal replication initiation protein.
 
 0.676
Smed_0429
TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: sme:SMc00888 putative contains A 2-component receiver domain protein.
 
 
 
 0.659
Smed_0637
TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sme:SMc02365 protease precursor protein; Belongs to the peptidase S1C family.
  
 0.645
Smed_3280
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sit:TM1040_3232 two component transcriptional regulator, winged helix family.
 
 
 0.639
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.