| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Smed_0128 | argB | Smed_0128 | Smed_0075 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.953 |
| Smed_0128 | argC | Smed_0128 | Smed_0859 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.928 |
| Smed_0128 | argD | Smed_0128 | Smed_0127 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: sme:SMc02138 putative acetylornithine aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.979 |
| Smed_0128 | argG | Smed_0128 | Smed_3063 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: argininosuccinate synthase; KEGG: sme:SMc03826 probable argininosuccinate synthase protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.995 |
| Smed_0128 | argH | Smed_0128 | Smed_2536 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: sme:SMc00725 probable argininosuccinate lyase ASAL protein. | 0.953 |
| Smed_0128 | argJ | Smed_0128 | Smed_2516 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.992 |
| Smed_0128 | carA | Smed_0128 | Smed_2229 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: sme:SMc01569 probable carbamoyl-phosphate synthetase, glutamine-hydrolyzing protein; Belongs to the CarA family. | 0.990 |
| Smed_0128 | carB | Smed_0128 | Smed_1257 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sme:SMc01215 probable carbamoyl-phosphate synthase large chain (ammonia chain arginine biosynthesis) protein; Belongs to the CarB family. | 0.992 |
| Smed_0860 | argC | Smed_0860 | Smed_0859 | TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: sme:SMc01802 probable agmatinase protein; Belongs to the arginase family. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.604 |
| Smed_0860 | argD | Smed_0860 | Smed_0127 | TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: sme:SMc01802 probable agmatinase protein; Belongs to the arginase family. | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: sme:SMc02138 putative acetylornithine aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.448 |
| argB | Smed_0128 | Smed_0075 | Smed_0128 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.953 |
| argB | argC | Smed_0075 | Smed_0859 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.996 |
| argB | argD | Smed_0075 | Smed_0127 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: sme:SMc02138 putative acetylornithine aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.961 |
| argB | argG | Smed_0075 | Smed_3063 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | PFAM: argininosuccinate synthase; KEGG: sme:SMc03826 probable argininosuccinate synthase protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.954 |
| argB | argH | Smed_0075 | Smed_2536 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: sme:SMc00725 probable argininosuccinate lyase ASAL protein. | 0.959 |
| argB | argJ | Smed_0075 | Smed_2516 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
| argB | carA | Smed_0075 | Smed_2229 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: sme:SMc01569 probable carbamoyl-phosphate synthetase, glutamine-hydrolyzing protein; Belongs to the CarA family. | 0.732 |
| argB | carB | Smed_0075 | Smed_1257 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: sme:SMc01215 probable carbamoyl-phosphate synthase large chain (ammonia chain arginine biosynthesis) protein; Belongs to the CarB family. | 0.837 |
| argB | glgC | Smed_0075 | Smed_2741 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.826 |
| argC | Smed_0128 | Smed_0859 | Smed_0128 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.928 |