STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_2016KEGG: mlo:msl1453 hypothetical protein. (61 aa)    
Predicted Functional Partners:
Smed_2017
HflC protein; HflC and HflK could regulate a protease.
     
 0.805
Smed_2018
HflK protein; HflC and HflK could encode or regulate a protease.
     
 0.805
Smed_2015
PFAM: amino acid-binding ACT domain protein; KEGG: sme:SMc01439 hypothetical protein.
       0.786
Smed_3262
KEGG: sme:SMc02573 hypothetical protein.
  
     0.645
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
     
 0.533
Smed_2019
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.513
Smed_3245
PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: sme:SMc02757 hypothetical protein.
 
   
 0.478
Smed_2515
PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02449 putative acetyltransferase protein.
  
     0.469
Smed_0163
KEGG: sme:SMc02247 conserved hypothetical signal peptide protein.
  
     0.467
Smed_2014
TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sme:SMc01438 putative protease precursor signal peptide protein; Belongs to the peptidase S1C family.
       0.465
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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