STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_2018HflK protein; HflC and HflK could encode or regulate a protease. (362 aa)    
Predicted Functional Partners:
Smed_2017
HflC protein; HflC and HflK could regulate a protease.
 
 
0.993
Smed_1202
PFAM: peptidase M41; AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: rle:RL1930 putative ATP-dependent hydrolase protein; Belongs to the AAA ATPase family.
  
 0.902
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.902
hflX
GTP-binding protein HSR1-related; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.823
Smed_2016
KEGG: mlo:msl1453 hypothetical protein.
     
 0.805
Smed_2015
PFAM: amino acid-binding ACT domain protein; KEGG: sme:SMc01439 hypothetical protein.
       0.786
yidC
60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.710
Smed_2704
PFAM: band 7 protein; KEGG: sme:SMc04020 hypothetical protein.
  
   
 0.627
Smed_2014
TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sme:SMc01438 putative protease precursor signal peptide protein; Belongs to the peptidase S1C family.
  
 
 0.541
Smed_0535
PFAM: peptidase M16 domain protein; KEGG: sme:SMc00451 putative processing protease protein; Belongs to the peptidase M16 family.
  
 0.523
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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