STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_2213Transcriptional regulator, SARP family; KEGG: sme:SMc01543 hypothetical protein. (612 aa)    
Predicted Functional Partners:
Smed_2211
PFAM: protein of unknown function DUF181; KEGG: sme:SMc01541 hypothetical protein.
 
    0.936
Smed_2656
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc03985 probable adenylate/guanylate cyclase protein.
 
 
 0.829
Smed_2212
KEGG: sme:SMc01542 hypothetical protein.
       0.785
Smed_0479
PFAM: protein of unknown function DUF1217; KEGG: sme:SMc00986 hypothetical protein.
  
 
   0.735
Smed_1990
PFAM: protein of unknown function DUF181; KEGG: sme:SMc01413 hypothetical protein.
 
    0.733
Smed_1538
PFAM: chemotaxis sensory transducer; KEGG: sme:SMc00190 hypothetical protein.
  
 0.726
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.710
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.706
Smed_1991
SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc01491 conserved hypothetical protein.
 
 
 0.695
Smed_1989
PFAM: TfuA domain protein core; KEGG: sme:SMc01412 hypothetical protein.
 
     0.686
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.