STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_2254PFAM: protein of unknown function DUF152; KEGG: sme:SMc02683 conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (264 aa)    
Predicted Functional Partners:
Smed_2255
Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: sme:SMc02684 putative hydrolase/peptidase protein.
       0.800
Smed_3197
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.763
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
     0.627
Smed_2253
PFAM: protein of unknown function DUF185; KEGG: sme:SMc02682 hypothetical protein.
       0.554
Smed_2256
KEGG: sme:SMc02685 hypothetical protein.
       0.487
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
     0.437
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.435
Smed_2083
TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: sme:SMc01865 probable cell division protein FTSW peptidoglycan synthesis; Belongs to the SEDS family.
 
  
 0.425
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.