STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_2276PFAM: protein of unknown function DUF58; KEGG: sme:SMc02704 hypothetical protein. (306 aa)    
Predicted Functional Partners:
Smed_2275
PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: sme:SMc02703 methanol dehydrogenase regulatory protein.
  
 0.980
Smed_2277
TIGRFAM: conserved hypothetical membrane protein; KEGG: sme:SMc02705 hypothetical protein.
 
    0.953
Smed_2278
KEGG: sme:SMc02706 hypothetical protein.
 
     0.948
Smed_2539
KEGG: sme:SMc00722 hypothetical protein.
  
   
 0.772
Smed_2279
PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01545 hypothetical protein.
       0.757
Smed_1124
PFAM: Domain of unknown function DUF1849; KEGG: sme:SMc02102 hypothetical protein.
  
     0.659
Smed_0045
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: sme:SMc01110 DNA-binding protein.
  
     0.576
Smed_2274
PFAM: protein of unknown function DUF1285; KEGG: sme:SMc02702 hypothetical protein.
 
     0.516
Smed_2272
PFAM: Polynucleotide adenylyltransferase region; KEGG: sme:SMc02700 tRNA nucleotidyltransferase (CCA-adding enzyme); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
     0.492
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
     
 0.447
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.