STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureEUreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (154 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.995
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.991
ureC
TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3; KEGG: sme:SMc01837 urease alpha subunit protein; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.979
ureB
TIGRFAM: urease, beta subunit; PFAM: Urease beta subunit; KEGG: sme:SMc01939 urease beta subunit protein; Belongs to the urease beta subunit family.
 
  
 0.976
ureA
TIGRFAM: urease, gamma subunit; PFAM: Urease gamma subunit region; KEGG: sme:SMc01941 urease gamma subunit protein; Belongs to the urease gamma subunit family.
 
  
 0.969
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.944
Smed_2380
PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sme:SMc01833 hypothetical protein.
       0.800
FlgF
PFAM: flagellar basal body rod protein; KEGG: sme:SMc03024 flagellar basal-body rod protein; Belongs to the flagella basal body rod proteins family.
      
 0.634
xylA
TIGRFAM: xylose isomerase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc03163 xylose isomerase; Belongs to the xylose isomerase family.
      
 0.634
Smed_2711
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sme:SMc04028 probable glutamate synthase NADPH large chain protein.
     
 0.511
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.