STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_2779TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: sme:SMc03153 keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase. (212 aa)    
Predicted Functional Partners:
edd
6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
 
 0.981
Smed_2321
PFAM: PfkB domain protein; KEGG: sme:SMc01531 putative 2-dehydro-3-deoxygluconokinase protein.
 
 
 0.942
Smed_2464
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: sme:SMc02043 probable KHG/KDPG aldolase (includes: 4-hydroxy-2-oxoglutarate aldolase, 2-dehydro-3-deoxyphosphogluconate aldolase) protein.
  
  
 
0.913
Smed_0394
D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00832 probable glycolate oxidase subunit protein.
   
 
 0.904
Smed_0395
PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00833 probable glycolate oxidase subunit protein.
   
 
 0.904
Smed_0308
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sme:SMc00768 isocitrate lyase.
     
 0.903
Smed_0396
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: sme:SMc00926 probable glycolate oxidase iron-sulfur subunit protein.
     
 0.903
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
     
 0.903
Smed_2390
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc01943 2-hydroxyacid dehydrogenase.
    
  0.902
Smed_3362
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc02828 putative hydroxyacid dehydrogenase protein.
    
  0.902
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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