STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_2831TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: sme:SMc03206 maleylacetoacetate isomerase (glutathione transferase ZETA 1) protein. (213 aa)    
Predicted Functional Partners:
Smed_2832
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sme:SMc03207 putative aromatic amino acid degradation protein.
 
 
 0.994
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 
 0.994
Smed_2836
TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc03211 putative 4-hydroxyphenylpyruvate dioxygenase protein.
 
  
 0.883
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.815
Smed_2834
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: sme:SMc03209 putative transcription regulator protein.
 
     0.792
Smed_3505
PFAM: Glutathione S-transferase domain; KEGG: sme:SMc00383 putative glutathione S-transferase protein.
  
 
 
 0.772
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.725
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.715
Smed_1692
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sme:SMc04240 hypothetical protein.
  
 
 0.664
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.615
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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