STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_3166KEGG: sme:SMc04392 putative dehydrogenase transmembrane protein. (506 aa)    
Predicted Functional Partners:
Smed_3165
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc04391 3-ketoacyl-(acyl-carrier-protein) reductase.
 
     0.837
Smed_3169
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04395 putative transport system permease ABC transporter protein.
 
     0.823
Smed_0591
Gluconate 2-dehydrogenase (acceptor); KEGG: sme:SMc00086 putative diheme cytochrome c-type signal peptide protein.
 
 
 0.816
Smed_3167
PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc04393 putative ATP-binding ABC transporter protein.
 
     0.812
Smed_3168
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04394 putative transport system permease ABC transporter protein.
 
     0.812
Smed_3174
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc04400 putative oxidoreductase protein.
 
    0.792
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
      
 0.634
clpP-2
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
      
 0.634
clpP-3
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
      
 0.634
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
  
 0.634
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.