| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Smed_3201 | Smed_3202 | Smed_3201 | Smed_3202 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB; Belongs to the ParB family. | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA. | 0.985 |
| Smed_3201 | mnmE | Smed_3201 | Smed_3205 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB; Belongs to the ParB family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.752 |
| Smed_3201 | mnmG | Smed_3201 | Smed_3204 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB; Belongs to the ParB family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.735 |
| Smed_3201 | polA | Smed_3201 | Smed_3381 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB; Belongs to the ParB family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.563 |
| Smed_3201 | rsmG | Smed_3201 | Smed_3203 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB; Belongs to the ParB family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.891 |
| Smed_3202 | Smed_3201 | Smed_3202 | Smed_3201 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA. | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB; Belongs to the ParB family. | 0.985 |
| Smed_3202 | mnmE | Smed_3202 | Smed_3205 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.557 |
| Smed_3202 | mnmG | Smed_3202 | Smed_3204 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.776 |
| Smed_3202 | rpsT | Smed_3202 | Smed_0001 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.732 |
| Smed_3202 | rsmG | Smed_3202 | Smed_3203 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.865 |
| ftsY | mnmE | Smed_3091 | Smed_3205 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.496 |
| ftsY | mnmG | Smed_3091 | Smed_3204 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.531 |
| ftsY | polA | Smed_3091 | Smed_3381 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.555 |
| ftsY | rsmG | Smed_3091 | Smed_3203 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.545 |
| ftsY | yidC | Smed_3091 | Smed_0079 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.415 |
| mnmE | Smed_3201 | Smed_3205 | Smed_3201 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB; Belongs to the ParB family. | 0.752 |
| mnmE | Smed_3202 | Smed_3205 | Smed_3202 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA. | 0.557 |
| mnmE | ftsY | Smed_3205 | Smed_3091 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.496 |
| mnmE | mnmG | Smed_3205 | Smed_3204 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.994 |
| mnmE | polA | Smed_3205 | Smed_3381 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.463 |