STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_3245PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: sme:SMc02757 hypothetical protein. (504 aa)    
Predicted Functional Partners:
Smed_3244
PFAM: Nucleotidyl transferase; KEGG: sme:SMc02758 putative nucleotidyl transferase protein.
 
 
 0.988
Smed_0037
PFAM: peptidase M22 glycoprotease; KEGG: sme:SMc01118 hypothetical protein.
  
 
 0.960
glmU
Nucleotidyl transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
    
 0.931
Smed_1160
Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein.
    
 0.926
Smed_3412
PFAM: ROK family protein; KEGG: sme:SMc02880 hypothetical protein.
    
  0.901
tsaD
Putative metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.899
Smed_3246
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02756 putative sensor histidine kinase protein.
 
     0.898
Smed_3242
TIGRFAM: Double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; KEGG: sme:SMc02760 putative ATP-dependent nuclease/helicase protein; Belongs to the helicase family. UvrD subfamily.
 
   
 0.861
Smed_3243
TIGRFAM: Double-strand break repair protein AddB; KEGG: sme:SMc02759 hypothetical protein.
 
     0.847
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 
 0.793
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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