node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GltA | Smed_1077 | Smed_1144 | Smed_1077 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.552 |
GltA | Smed_1078 | Smed_1144 | Smed_1078 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.961 |
GltA | Smed_2676 | Smed_1144 | Smed_2676 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: sme:SMc04005 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.454 |
GltA | Smed_2711 | Smed_1144 | Smed_2711 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sme:SMc04028 probable glutamate synthase NADPH large chain protein. | 0.896 |
GltA | Smed_3037 | Smed_1144 | Smed_3037 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: vei:Veis_2228 alpha/beta hydrolase fold. | 0.961 |
GltA | Smed_3139 | Smed_1144 | Smed_3139 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.953 |
GltA | eno | Smed_1144 | Smed_1072 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.518 |
GltA | mdh | Smed_1144 | Smed_2944 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.991 |
GltA | pckA | Smed_1144 | Smed_3253 | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.974 |
Smed_0548 | Smed_1077 | Smed_0548 | Smed_1077 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.951 |
Smed_0548 | Smed_2676 | Smed_0548 | Smed_2676 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: sme:SMc04005 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.934 |
Smed_0548 | Smed_2711 | Smed_0548 | Smed_2711 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sme:SMc04028 probable glutamate synthase NADPH large chain protein. | 0.518 |
Smed_0548 | Smed_3139 | Smed_0548 | Smed_3139 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.937 |
Smed_0548 | eno | Smed_0548 | Smed_1072 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.935 |
Smed_0548 | mdh | Smed_0548 | Smed_2944 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.470 |
Smed_0548 | pckA | Smed_0548 | Smed_3253 | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.934 |
Smed_1077 | GltA | Smed_1077 | Smed_1144 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: sme:SMc02087 citrate synthase; Belongs to the citrate synthase family. | 0.552 |
Smed_1077 | Smed_0548 | Smed_1077 | Smed_0548 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: sme:SMc00025 putative pyruvate phosphate dikinase protein; Belongs to the PEP-utilizing enzyme family. | 0.951 |
Smed_1077 | Smed_1078 | Smed_1077 | Smed_1078 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.996 |
Smed_1077 | Smed_2676 | Smed_1077 | Smed_2676 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: sme:SMc04005 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.946 |