STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smed_3286PFAM: Sarcosine oxidase gamma subunit; KEGG: sme:SMc02605 putative sarcosine oxidase gamma subunit protein. (177 aa)    
Predicted Functional Partners:
Smed_2750
TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein barrel; KEGG: sme:SMc03931 putative sarcosine oxidase alpha subunit transmembrane protein.
 0.997
Smed_3287
TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc02606 putative sarcosine oxidase alpha subunit transmembrane protein.
 
 0.996
Smed_2751
TIGRFAM: sarcosine oxidase, delta subunit family; PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: sme:SMc03932 putative sarcosine oxidase delta subunit protein.
 
 0.988
Smed_2198
PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc01663 putative dimethylglycine dehydrogenase precursor; Belongs to the GcvT family.
 
 0.979
Smed_3288
TIGRFAM: sarcosine oxidase, delta subunit family; PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: sme:SMc02607 sarcosine oxidase delta subunit protein.
 
 
 0.978
Smed_2749
TIGRFAM: sarcosine oxidase, gamma subunit family; PFAM: Sarcosine oxidase gamma subunit; KEGG: sme:SMc03930 putative sarcosine oxidase gamma subunit protein.
  
  
  0.944
Smed_2752
TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc03933 putative sarcosine oxidase subunit B protein.
 
 0.944
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.909
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.907
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.907
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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