STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1V6USA7DNA ligase. (819 aa)    
Predicted Functional Partners:
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.968
A0A1V6ULL7
Vezatin domain-containing protein.
   
 0.954
A0A1V6UMD0
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.954
A0A1V6V1Q3
DNA polymerase.
   
 0.929
A0A1V6UFY3
AAA domain-containing protein.
   
 0.916
A0A1V6V990
ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.
   
 0.905
A0A1V6UTQ3
DNA ligase.
  
  
 
0.897
A0A1V6UNW4
SAP domain-containing protein.
   
 0.879
A0A1V6UFS5
Uncharacterized protein.
  
 0.843
A0A1V6U852
AAA domain-containing protein.
   
 0.836
Your Current Organism:
Penicillium coprophilum
NCBI taxonomy Id: 36646
Other names: P. coprophilum, Penicillium coprophilum var. coprophilum
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