STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1V6UUC5POLXc domain-containing protein. (656 aa)    
Predicted Functional Partners:
A0A1V6UHL7
BRCT domain-containing protein.
     
0.898
A0A1V6UNW4
SAP domain-containing protein.
    
 0.823
A0A1V6V6E8
Uncharacterized protein.
    
 0.822
A0A1V6V3K0
DNA ligase.
  
 0.817
A0A1V6USA7
DNA ligase.
  
 0.814
A0A1V6UTQ3
DNA ligase.
  
 0.814
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.808
A0A1V6UAM4
DNA_LIGASE_A3 domain-containing protein.
  
 0.799
A0A1V6UFS5
Uncharacterized protein.
   
 0.785
A0A1V6UFY5
Endo/exonuclease/phosphatase domain-containing protein.
    
 0.751
Your Current Organism:
Penicillium coprophilum
NCBI taxonomy Id: 36646
Other names: P. coprophilum, Penicillium coprophilum var. coprophilum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.