STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDF45129.1ATP-dependent Zn proteases; Belongs to the AAA ATPase family. (796 aa)    
Predicted Functional Partners:
SDF03018.1
SPFH domain, Band 7 family protein.
   
 0.942
SDF67979.1
SPFH domain / Band 7 family protein.
   
 0.942
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.882
rplB
Large subunit ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.880
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.876
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.871
rpsI
Small subunit ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
 
   0.867
rpmA
LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.867
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.863
rplQ
Large subunit ribosomal protein L17.
   
 
 0.863
Your Current Organism:
Pseudonocardia oroxyli
NCBI taxonomy Id: 366584
Other names: CGMCC 4.3143, DSM 44984, JCM 13909, P. oroxyli, Pseudonocardia oroxyli Gu et al. 2006, Pseudonocardia sp. D10, strain D10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.