STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDF57802.1Protein of unknown function. (186 aa)    
Predicted Functional Partners:
prcA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
  
 
 
 0.998
prcB
Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
  
 
 
 0.983
SDF57720.1
ABC-2 type transport system ATP-binding protein.
     
 0.838
SDF57759.1
ABC-2 type transport system permease protein.
     
 0.834
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
   
 0.799
SDF57677.1
rhamnopyranosyl-N-acetylglucosaminyl-diphospho- decaprenol beta-1,3/1,4-galactofuranosyltransferase.
     
 0.780
SDF57848.1
Putative NAD(P)H quinone oxidoreductase, PIG3 family.
       0.777
pafA
Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
  
   
 0.719
SDF57639.1
Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose).
       0.701
SDF00277.1
Proteasome accessory factor A.
  
   
 0.656
Your Current Organism:
Pseudonocardia oroxyli
NCBI taxonomy Id: 366584
Other names: CGMCC 4.3143, DSM 44984, JCM 13909, P. oroxyli, Pseudonocardia oroxyli Gu et al. 2006, Pseudonocardia sp. D10, strain D10
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