node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDE61847.1 | SDF05311.1 | SAMN05216377_101347 | SAMN05216377_103150 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Glucose-6-phosphate isomerase. | 0.984 |
SDE61847.1 | SDG30158.1 | SAMN05216377_101347 | SAMN05216377_110202 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.977 |
SDE61847.1 | eno | SAMN05216377_101347 | SAMN05216377_109244 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.999 |
SDE61847.1 | guaA | SAMN05216377_101347 | SAMN05216377_102429 | Pyruvate kinase; Belongs to the pyruvate kinase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.449 |
SDE61847.1 | pfp | SAMN05216377_101347 | SAMN05216377_106190 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.913 |
SDE61847.1 | pgi | SAMN05216377_101347 | SAMN05216377_11954 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.993 |
SDE61847.1 | tal | SAMN05216377_101347 | SAMN05216377_103149 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.962 |
SDE61847.1 | tpiA | SAMN05216377_101347 | SAMN05216377_103161 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.956 |
SDF05311.1 | SDE61847.1 | SAMN05216377_103150 | SAMN05216377_101347 | Glucose-6-phosphate isomerase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.984 |
SDF05311.1 | SDF86327.1 | SAMN05216377_103150 | SAMN05216377_107141 | Glucose-6-phosphate isomerase. | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. | 0.813 |
SDF05311.1 | SDF96414.1 | SAMN05216377_103150 | SAMN05216377_10840 | Glucose-6-phosphate isomerase. | Fructose-1,6-bisphosphatase II. | 0.937 |
SDF05311.1 | SDG30158.1 | SAMN05216377_103150 | SAMN05216377_110202 | Glucose-6-phosphate isomerase. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.976 |
SDF05311.1 | eno | SAMN05216377_103150 | SAMN05216377_109244 | Glucose-6-phosphate isomerase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.985 |
SDF05311.1 | pfp | SAMN05216377_103150 | SAMN05216377_106190 | Glucose-6-phosphate isomerase. | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.917 |
SDF05311.1 | tal | SAMN05216377_103150 | SAMN05216377_103149 | Glucose-6-phosphate isomerase. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.994 |
SDF05311.1 | tpiA | SAMN05216377_103150 | SAMN05216377_103161 | Glucose-6-phosphate isomerase. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.989 |
SDF86327.1 | SDF05311.1 | SAMN05216377_107141 | SAMN05216377_103150 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. | Glucose-6-phosphate isomerase. | 0.813 |
SDF86327.1 | SDF96414.1 | SAMN05216377_107141 | SAMN05216377_10840 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. | Fructose-1,6-bisphosphatase II. | 0.849 |
SDF86327.1 | SDG30158.1 | SAMN05216377_107141 | SAMN05216377_110202 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.910 |
SDF86327.1 | pfp | SAMN05216377_107141 | SAMN05216377_106190 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.813 |