Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caul_3000PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: ccr:CC_2179 propionyl-CoA carboxylase, alpha subunit. (669 aa)    
Predicted Functional Partners:
Caul_2999
PFAM: carboxyl transferase; KEGG: ccr:CC_1975 propionyl-CoA carboxylase beta chain.
 0.994
Caul_1705
PFAM: carboxyl transferase; KEGG: ccr:CC_1975 propionyl-CoA carboxylase beta chain.
 0.977
Caul_4464
Pyruvate carboxylase., Methylmalonyl-CoA carboxytransferase; PFAM: carboxyl transferase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: ccr:CC_3214 carbamoyl-phosphate synthase/carboxyl transferase.
 
0.932
Caul_2759
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.923
Caul_0731
PFAM: HpcH/HpaI aldolase; KEGG: ccr:CC_2999 citrate lyase, beta subunit, putative; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.922
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.920
Caul_1897
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: eba:p2A394 DitO-like thiolase, possibly related to diterpenoid metabolism; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.920
Caul_4010
KEGG: acr:Acry_1576 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.920
Caul_4752
acetyl-CoA acetyltransferase; KEGG: ccr:CC_3462 thiolase family protein; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.920
Caul_1872
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: swi:Swit_0780 catalytic domain of components of various dehydrogenase complexes.
  
 0.919
Your Current Organism:
Caulobacter sp. K31
NCBI taxonomy Id: 366602
Other names: C. sp. K31
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