STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCU03935Homoserine dehydrogenase. (365 aa)    
Predicted Functional Partners:
thr-4
Homoserine kinase.
  
 0.999
NCU04118
Aspartokinase.
 0.996
hom-1
Aspartate-semialdehyde dehydrogenase.
  
 0.995
NCU03425
Threonine synthase.
  
 0.993
met-5
Homoserine O-acetyltransferase.
 
 0.954
ilv-4
Acetolactate synthase small subunit.
  
  
 0.943
NCU00799
Homocysteine S-methyltransferase.
  
 
 0.937
met-2
Cystathionine beta-lyase; Involved in de novo synthesis of methionine. Belongs to the trans-sulfuration enzymes family.
  
 
 0.918
met-7
Cystathionine gamma-synthase; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia (By similarity).
  
 
 0.917
NCU05093
Cystathionine gamma-synthase.
  
 
 0.915
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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