node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ad-8 | lia1 | Q7S604 | Q7S891 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. | 0.653 |
NCU05076 | lia1 | Q7RWK8 | Q7S891 | Uncharacterized protein. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. | 0.657 |
NCU05454 | lia1 | F5HHQ6 | Q7S891 | Glycerol-3-phosphate dehydrogenase. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. | 0.745 |
NCU07922 | NCU09903 | Q7S9Z6 | Q7S0E4 | Elongation factor 3. | Elongation factor 3. | 0.998 |
NCU07922 | dys-1 | Q7S9Z6 | P49365 | Elongation factor 3. | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.402 |
NCU07922 | hex-1 | Q7S9Z6 | P87252 | Elongation factor 3. | Woronin body major protein; Major protein in the hexagonal crystals of Woronin bodies, a peroxisomal vesicle that seal the septal pore in response to cellular damage. | 0.792 |
NCU07922 | lia1 | Q7S9Z6 | Q7S891 | Elongation factor 3. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. | 0.745 |
NCU07922 | rad23 | Q7S9Z6 | Q7S306 | Elongation factor 3. | Rad23-like protein. | 0.992 |
NCU07922 | tif-51 | Q7S9Z6 | P38672 | Elongation factor 3. | Eukaryotic translation initiation factor 5A; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). | 0.796 |
NCU09903 | NCU07922 | Q7S0E4 | Q7S9Z6 | Elongation factor 3. | Elongation factor 3. | 0.998 |
NCU09903 | hex-1 | Q7S0E4 | P87252 | Elongation factor 3. | Woronin body major protein; Major protein in the hexagonal crystals of Woronin bodies, a peroxisomal vesicle that seal the septal pore in response to cellular damage. | 0.768 |
NCU09903 | lia1 | Q7S0E4 | Q7S891 | Elongation factor 3. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. | 0.790 |
NCU09903 | rad23 | Q7S0E4 | Q7S306 | Elongation factor 3. | Rad23-like protein. | 0.992 |
NCU09903 | tif-51 | Q7S0E4 | P38672 | Elongation factor 3. | Eukaryotic translation initiation factor 5A; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). | 0.768 |
dys-1 | NCU07922 | P49365 | Q7S9Z6 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Elongation factor 3. | 0.402 |
dys-1 | hex-1 | P49365 | P87252 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Woronin body major protein; Major protein in the hexagonal crystals of Woronin bodies, a peroxisomal vesicle that seal the septal pore in response to cellular damage. | 0.933 |
dys-1 | lia1 | P49365 | Q7S891 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. | 0.981 |
dys-1 | spe-1 | P49365 | P27121 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. | 0.732 |
dys-1 | tif-51 | P49365 | P38672 | Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Eukaryotic translation initiation factor 5A; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). | 0.999 |
hex-1 | NCU07922 | P87252 | Q7S9Z6 | Woronin body major protein; Major protein in the hexagonal crystals of Woronin bodies, a peroxisomal vesicle that seal the septal pore in response to cellular damage. | Elongation factor 3. | 0.792 |