STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prk-2Protein kinase Yak1. (938 aa)    
Predicted Functional Partners:
cdc5
Serine/threonine protein kinase.
    
 
0.958
cdc15
Cell division control protein 15.
    
  
0.956
NCU08878
TEM1.
   
 
 0.956
NCU06039
WD repeat protein.
   
 
 0.864
NCU07688
Rho GTPase activator Rga.
    
 
 0.805
dbf2
AGC/NDR protein kinase.
    
 
0.758
ssp-1
Peptidyl-prolyl cis-trans isomerase ssp-1; Site-specific PPIase with respect to the amino acid N- terminal to the proline residue. Peptides with glutamate, phosphoserine, or phosphothreonine in the -1 position are the best substrates. It is not only able to isomerize small peptides but is also active in protein folding.
    
 0.632
NCU09813
SMT3, variant 1.
    
 0.632
mus-21
Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity).
    
 0.629
NCU04302
Ubiquitin-conjugating enzyme E; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.627
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.