Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
addBATP-dependent helicase/deoxyribonuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1158 aa)    
Predicted Functional Partners:
addA
ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
 
 
 0.997
lexA_2
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response).
  
 
 0.928
sbcD
Nuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.764
speG
Spermidine N(1)-acetyltransferase.
       0.724
sbcC
Nuclease SbcCD subunit C.
 
  
 0.625
trmK
tRNA (adenine(22)-N(1))-methyltransferase.
 
     0.568
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
   
 0.506
yjbM
GTP pyrophosphokinase YjbM.
  
     0.491
AQR98221.1
Hypothetical protein.
  
     0.441
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
 0.418
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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