Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
esxAVirulence factor EsxA; Belongs to the WXG100 family. (100 aa)    
Predicted Functional Partners:
eccCa1
ESX-1 secretion system protein EccCa1.
 
 
 0.977
essB
Putative membrane protein essB.
 
  
 0.956
AQR92965.1
Hypothetical protein.
 
   
 0.790
spoIIIE
DNA translocase SpoIIIE.
  
 
 0.747
AQR92961.1
Hypothetical protein.
       0.668
AQR92962.1
YukD.
       0.668
AQR96402.1
Hypothetical protein.
  
     0.439
disA_2
DNA integrity scanning protein DisA; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
       0.413
AQR92959.1
YbbR-like protein.
       0.413
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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