Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
eamA_1Putative amino-acid metabolite efflux pump. (312 aa)    
Predicted Functional Partners:
rhaS_2
HTH-type transcriptional activator RhaS.
 
    0.913
devR
Transcriptional regulatory protein DevR (DosR).
     
 0.484
comP
Sensor histidine kinase ComP.
  
    0.475
drrA_1
Daunorubicin/doxorubicin resistance ATP-binding protein DrrA.
   
 
 0.452
AQR94428.1
Transcriptional regulator PadR-like family protein.
  
    0.438
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
    
  0.416
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
    
  0.416
AQR93229.1
ABC-2 family transporter protein.
  
  
 0.415
secY
Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.403
AQR93228.1
ABC-2 family transporter protein.
     
 0.402
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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