| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gpr | spo0A | CLSAP_09430 | CLSAP_25020 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.845 |
| gpr | spoIIAB_1 | CLSAP_09430 | CLSAP_09340 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.836 |
| gpr | spoIIP | CLSAP_09430 | CLSAP_09440 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein SpoIIP. | 0.932 |
| gpr | spoIVA | CLSAP_09430 | CLSAP_12420 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.843 |
| gpr | spoIVB | CLSAP_09430 | CLSAP_25010 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | SpoIVB peptidase precursor. | 0.857 |
| gpr | spoVAC1 | CLSAP_09430 | CLSAP_09360 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | SpoVA protein. | 0.884 |
| gpr | spoVAC2 | CLSAP_09430 | CLSAP_40990 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | SpoVA protein. | 0.883 |
| gpr | spoVAD_1 | CLSAP_09430 | CLSAP_09370 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage V sporulation protein AD. | 0.909 |
| gpr | spoVAD_2 | CLSAP_09430 | CLSAP_41000 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage V sporulation protein AD. | 0.908 |
| gpr | yyaC | CLSAP_09430 | CLSAP_06350 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Hypothetical protein. | 0.842 |
| spo0A | gpr | CLSAP_25020 | CLSAP_09430 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.845 |
| spo0A | spoIIAB_1 | CLSAP_25020 | CLSAP_09340 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.943 |
| spo0A | spoIIP | CLSAP_25020 | CLSAP_09440 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein SpoIIP. | 0.857 |
| spo0A | spoIVA | CLSAP_25020 | CLSAP_12420 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.870 |
| spo0A | spoIVB | CLSAP_25020 | CLSAP_25010 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | SpoIVB peptidase precursor. | 0.956 |
| spo0A | spoVAC1 | CLSAP_25020 | CLSAP_09360 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | SpoVA protein. | 0.775 |
| spo0A | spoVAC2 | CLSAP_25020 | CLSAP_40990 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | SpoVA protein. | 0.762 |
| spo0A | spoVAD_1 | CLSAP_25020 | CLSAP_09370 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage V sporulation protein AD. | 0.834 |
| spo0A | spoVAD_2 | CLSAP_25020 | CLSAP_41000 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage V sporulation protein AD. | 0.814 |
| spo0A | yyaC | CLSAP_25020 | CLSAP_06350 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Hypothetical protein. | 0.681 |