STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIPStage II sporulation protein SpoIIP. (356 aa)    
Predicted Functional Partners:
spoIIE
Stage II sporulation protein E.
  
   
 0.952
spoIIR
Stage II sporulation protein SpoIIR.
  
   
 0.950
gpr
Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
 
  
 0.932
spoIIAB_1
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.931
spoIIGA
Sporulation sigma-E factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
   
 0.910
spoIVB
SpoIVB peptidase precursor.
  
   
 0.905
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
   
 0.897
dacF_2
D-alanyl-D-alanine carboxypeptidase DacF precursor; Belongs to the peptidase S11 family.
  
  
 0.894
spoIIAA
Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
   
 0.881
spoIIM
Stage II sporulation protein M.
  
   
 0.875
Your Current Organism:
Clostridium saccharoperbutylacetonicum
NCBI taxonomy Id: 36745
Other names: ATCC 27021, C. saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum Keis et al. 2001, DSM 14923, NCIMB 12606, strain N1-4 (HMT)
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