| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQR93922.1 | sigF_2 | CLSAP_12290 | CLSAP_12280 | PRC-barrel domain protein. | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.855 |
| AQR93922.1 | spoIIE | CLSAP_12290 | CLSAP_01230 | PRC-barrel domain protein. | Stage II sporulation protein E. | 0.682 |
| AQR93922.1 | spoIIGA | CLSAP_12290 | CLSAP_12260 | PRC-barrel domain protein. | Sporulation sigma-E factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.811 |
| AQR93922.1 | spoIIID | CLSAP_12290 | CLSAP_06330 | PRC-barrel domain protein. | Stage III sporulation protein D. | 0.561 |
| AQR93922.1 | spoIIR | CLSAP_12290 | CLSAP_06020 | PRC-barrel domain protein. | Stage II sporulation protein SpoIIR. | 0.666 |
| AQR93922.1 | spoIVA | CLSAP_12290 | CLSAP_12420 | PRC-barrel domain protein. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.511 |
| AQR93922.1 | spoVT_1 | CLSAP_12290 | CLSAP_01110 | PRC-barrel domain protein. | Stage V sporulation protein T. | 0.421 |
| sigF_2 | AQR93922.1 | CLSAP_12280 | CLSAP_12290 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | PRC-barrel domain protein. | 0.855 |
| sigF_2 | spo0A | CLSAP_12280 | CLSAP_25020 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.941 |
| sigF_2 | spoIIAB_1 | CLSAP_12280 | CLSAP_09340 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.898 |
| sigF_2 | spoIIE | CLSAP_12280 | CLSAP_01230 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein E. | 0.943 |
| sigF_2 | spoIIGA | CLSAP_12280 | CLSAP_12260 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation sigma-E factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.918 |
| sigF_2 | spoIIID | CLSAP_12280 | CLSAP_06330 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein D. | 0.833 |
| sigF_2 | spoIIR | CLSAP_12280 | CLSAP_06020 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein SpoIIR. | 0.822 |
| sigF_2 | spoIVA | CLSAP_12280 | CLSAP_12420 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.836 |
| sigF_2 | spoVAD_1 | CLSAP_12280 | CLSAP_09370 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein AD. | 0.787 |
| sigF_2 | spoVT_1 | CLSAP_12280 | CLSAP_01110 | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein T. | 0.817 |
| spo0A | sigF_2 | CLSAP_25020 | CLSAP_12280 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.941 |
| spo0A | spoIIAB_1 | CLSAP_25020 | CLSAP_09340 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.937 |
| spo0A | spoIIE | CLSAP_25020 | CLSAP_01230 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein E. | 0.922 |
